Strecker Reaction of Ethyl Cyanoformate with Aldimines Catalyzed by N-Heterocyclic Carbene
نویسندگان
چکیده
منابع مشابه
N-Heterocyclic carbene-catalyzed [3+3] cyclocondensation of bromoenals with aldimines: highly enantioselective synthesis of dihydropyridinones.
The N-heterocyclic carbene-catalyzed [3+3] cyclocondensation of bromoenals and aldimines was developed to give the corresponding dihydropyridinones in good yields with excellent enantioselectivities.
متن کاملRh-N-heterocyclic carbene (NHC) complex-catalyzed addition of phenylboronic acid to N-sulfonyl and N-phosphinoyl aldimines.
Rh-N-heterocyclic carbene (NHC) complexes were generated in situ from imidazolium salts, [RhCl(cod)](2) and t-BuOK in dioxane. In the presence of a catalytic amount of Rh-NHC complexes, the addition reaction of phenylboronic acid to N-sulfonylarylimines and N-phosphinyolarylimines gave the corresponding amines in high yields.
متن کاملN-heterocyclic carbene-catalyzed aza-Michael addition.
Aza-Michael addition of amines, including aromatic and aliphatic amines, with α, β-unsaturated ketones was realized employing N-Heterocyclic Carbene (NHC) as organocatalyst, yielding β-amino ketones with up to 98% yield.
متن کاملN-Heterocyclic Carbene Catalyzed Enantioselective Annulation of Benzothiazolyl Ethyl Acetates with 2-Bromoenals.
An N-heterocyclic carbene catalyzed enantioselective [3+3] annulation of benzothiazolyl acetates with 2-bromoenals has been developed. The protocol provides a direct asymmetric synthesis of dihydro-1H-benzothiazolopyridinones in good to very good yields and medium ee values. In many cases, the virtually enantiopure heterocycles are available through a single recrystallization (99% ee).
متن کاملAsymmetric esterification of ketenes catalyzed by an N-heterocyclic carbene.
The chiral N-heterocyclic carbene precursor, derived from L-pyroglutamic acid, was found to be an efficient precatalyst for the enantioselective esterification of alkylarylketenes with benzhydrol to give the corresponding esters in good yields with good to high enantioselectivities (up to 95% ee).
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ژورنال
عنوان ژورنال: Chinese Journal of Organic Chemistry
سال: 2017
ISSN: 0253-2786
DOI: 10.6023/cjoc201610029